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Antibody conjugates and therapeutic strategies

McCarron, Paul, Olwill, S. A., Marouf, W. M. Y., Buick, R. J., Walker, B. and Scott, C. J. (2005) Antibody conjugates and therapeutic strategies. Molecular Interventions, 5 (6). pp. 368-380. [Journal article]

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Immunotherapeutics represent the largest group of molecules currently in development as new drug entities. These versatile molecules are being investigated for the treatment of a range of pathological conditions including cancer, infectious and inflammatory diseases. Antibodies can be used to exert biological effects themselves or as delivery agents of conjugated drug molecules. Site-specific delivery of therapeutic agents has been an ultimate goal of the pharmaceutical industry in order to maximize drug action and minimize side effects. Antibodies have the potential to realize this objective and in this review we will examine some of the main strategies currently being employed for the development of these diverse therapeutic molecules.

Item Type:Journal article
Faculties and Schools:Faculty of Life and Health Sciences > School of Pharmacy and Pharmaceutical Science
Faculty of Life and Health Sciences
Research Institutes and Groups:Biomedical Sciences Research Institute
Biomedical Sciences Research Institute > Pharmacy & Pharmaceutical Sciences
ID Code:1165
Deposited By: Professor Paul McCarron
Deposited On:22 May 2017 14:43
Last Modified:22 May 2017 14:43

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