Dixon, D and Manson, J (2010) The Influence of Solvent Processing on Polyester Bioabsorable Polymers. Journal of Biomaterials Applications, 00 . [Journal article]
- Published Version
Indefinitely restricted to Repository staff only.
Solvent-based methods are commonly employed for the production of polyester-based samples and coatings in both medical device production and research. The influence of solvent casting and subsequent drying time was studied using thermal analysis, spectroscopy and weight measurement for four grades of 50 : 50 poly(lactic-co-glycolic acid) (PLGA) produced by using chloroform, dichloromethane, and acetone. The results demonstrate that solvent choice and PLGA molecular weight are critical factors in terms of solvent removal rate and maintaining sample integrity, respectively. The protocols widely employed result in high levels of residual solvent and a new protocol is presented together with solutions to commonly encountered problems.
|Item Type:||Journal article|
|Faculties and Schools:||Faculty of Computing & Engineering|
Faculty of Computing & Engineering > School of Engineering
|Research Institutes and Groups:||Engineering Research Institute|
Engineering Research Institute > Nanotechnology & Integrated BioEngineering Centre (NIBEC)
|Deposited By:||Dr Dorian Dixon|
|Deposited On:||27 Jul 2010 10:18|
|Last Modified:||09 Dec 2015 10:49|
Available Versions of this Item
- The Influence of Solvent Processing on Polyester Bioabsorable Polymers. (deposited 27 Jul 2010 10:18) [Currently Displayed]
Repository Staff Only: item control page