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Microbubble-sonosensitiser conjugates as therapeutics in sonodynamic therapy

Nomikou, Nikolitsa, Fowley, Colin, Byrne, Niall M., McCaughan, Bridgeen, MCHALE, AP and Callan, John F. (2012) Microbubble-sonosensitiser conjugates as therapeutics in sonodynamic therapy. CHEMICAL COMMUNICATIONS, 48 (67). pp. 8332-8334. [Journal article]

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DOI: 10.1039/c2cc33913g

Abstract

A Rose Bengal sonosensitiser has been covalently attached to a lipid microbubble and the resulting conjugate shown to produce higher levels of singlet oxygen, enhanced cytotoxicity in a cancer cell line and a greater reduction in tumour growth than the sonosensitiser alone.

Item Type:Journal article
Faculties and Schools:Faculty of Life and Health Sciences > School of Pharmacy and Pharmaceutical Science
Faculty of Life and Health Sciences
Research Institutes and Groups:Biomedical Sciences Research Institute
Biomedical Sciences Research Institute > Pharmaceutical Science and Practice
ID Code:23453
Deposited By: Professor John Callan
Deposited On:27 Sep 2012 12:32
Last Modified:13 May 2014 13:22

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