Ulster University Logo

Profiling of phenols in human fecal water after raspberry supplementation.

Gill, C.I.R, McDougall, Gordon J, Glidewell, Sheila, Stewart, Derek, Shen, Qing, Tuohy, Kieran, Dobbin, Aine, Boyd, Adele, Brown, Emma, Haldar, Sumanto and Rowland, Ian R (2010) Profiling of phenols in human fecal water after raspberry supplementation. Journal of agricultural and food chemistry, 58 (19). pp. 10389-95. [Journal article]

Full text not available from this repository.

Abstract

The phenolic compositions of fecal water samples from ten free-living human subjects without marked dietary restrictions were monitored before and after intake of raspberry puree (200 g/day, 4 days) using gas chromatography-mass spectrometry. No single phenolic component was increased in all subjects after intake, but a majority of subjects had significant elevations in phenylacetic acid (7/10), 4-hydroxyphenylacetic acid (6/10), 3-hydroxyphenylacetic acid (5/10), 3-phenylpropionic acid and 3-(4-hydroxyphenyl)propionic acid. The levels of 3,4-dihydroxbenzoic acid were elevated in 8/10 subjects, significantly for 6 subjects (p < 0.05), and not significantly reduced in the other 2 subjects. In addition, unlike most other fecal metabolites, the increase was always >2-fold. This metabolite may be representative of the increased colonic dose of cyanidin anthocyanins. The colonic microbiota varied greatly between individuals, and supplementation with raspberries did not produce any statistically significant alterations in the profile of colonic bacteria, nor was a common pattern revealed to account for the interindividual variations observed in the fecal water phenolic profiles.

Item Type:Journal article
Faculties and Schools:Faculty of Life and Health Sciences > School of Biomedical Sciences
Faculty of Life and Health Sciences
Research Institutes and Groups:Biomedical Sciences Research Institute > Nutrition Innovation Centre for Food and Health (NICHE)
Biomedical Sciences Research Institute
ID Code:24488
Deposited By: Dr Emma Brown
Deposited On:15 Jan 2013 13:56
Last Modified:15 Jan 2013 13:56

Repository Staff Only: item control page