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Biodegradation of lindane by Pleurotus ostreatus via central composite design

Rigas, F, Dritsa, V, Marchant, R, Papadopoulou, K, Avramides, EJ and Hatzianestis, I (2005) Biodegradation of lindane by Pleurotus ostreatus via central composite design. ENVIRONMENT INTERNATIONAL, 31 (2). pp. 191-196. [Journal article]

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DOI: 10.1016/j.envint.2004.09.024


The degradation of lindane was studied in liquid-agitated cultures using a commercial strain of the fungus Pleurotus ostreatus as the biodegrading organism. The biodegradation was accomplished with the action of extracellular oxidative enzymes, produced by the fungus to decompose woody substrates. Enzyme activities of manganese peroxidase and laccase were measured in a liquid mineral medium. An orthogonal Central Composite Design of experiments was used to construct second-order response surfaces with the fungus growth, final pH and the lindane biodegradation as optimization parameters. The initial lindane concentration, the nitrogen content, the incubation time and the temperature were used as design factors. Optimal conditions found for all these parameters will be used for the continuation of this project aiming at the bioremediation of contaminated sites with persistent organic pollutants such as lindane. (C) 2004 Elsevier Ltd. All rights reserved.

Item Type:Journal article
Faculties and Schools:Faculty of Life and Health Sciences > School of Biomedical Sciences
Research Institutes and Groups:Biomedical Sciences Research Institute
ID Code:2703
Deposited By: Professor Roger Marchant
Deposited On:15 Dec 2009 20:43
Last Modified:15 Oct 2012 08:15

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