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An Overview of Matrix-Assisted Laser Desorption/Ionization (MALDI) Mass Spectrometry and Some of Its Applications

Duncan, Mark W, Gibson, David, Walsh, Ryan, Massod, Afsham and Benabdelkamel, Hicham (2014) An Overview of Matrix-Assisted Laser Desorption/Ionization (MALDI) Mass Spectrometry and Some of Its Applications. In: Detection of Chemical, Biological, Radiological and Nuclear Agents for the Prevention of Terrorism, NATO Science for Peace and Security Series A: Chemistry and Biology. Springer Science, Dordrecht, Germany, pp. 69-81. ISBN 978-94-017-9237-0 [Book section]

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URL: http://link.springer.com/chapter/10.1007/978-94-017-9238-7_5#page-1

DOI: 10.1007/978-94-017-9238-7_5

Abstract

Matrix-assisted laser desorption/ionization time-of-flight (TOF) mass spectrometry (MS) is a powerful tool for both the qualitative and quantitative analysis of wide array of analytes. MALDI-TOF MS is simple, both in design and practice, and offers the advantages that analysis times are very short, the mass range is virtually unlimited, and sensitivity is high. This chapter describes the theory and practice of MALDI and illustrates the utility of approach by reviewing its commonapplications.

Item Type:Book section
Faculties and Schools:Faculty of Life and Health Sciences > School of Biomedical Sciences
Faculty of Life and Health Sciences
Research Institutes and Groups:Biomedical Sciences Research Institute
Biomedical Sciences Research Institute > Stratified Medicine
ID Code:29974
Deposited By: Dr David Gibson
Deposited On:16 Dec 2014 09:37
Last Modified:16 Dec 2014 09:37

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