Ulster University Logo

Tracking (Poly)phenol components from raspberries in ileal fluid.

Mc Dougall, Gordon, Connor, Sean, Pereira-Caro, Gemma, Gonzalez-Barrio, Rocio, Brown, Emma, Verrall, Susan, Lawther, Roger, Rowland, Ian, Stewart, Derek, Crozier, Alan and Gill, Chris IR (2014) Tracking (Poly)phenol components from raspberries in ileal fluid. J Agric Food Chem., 62 (30). pp. 7631-7641. [Journal article]

Full text not available from this repository.

DOI: doi: 10.1021/jf502259j


The (poly)phenols in ileal fluid after ingestion of raspberries were analyzed by targeted and nontargeted LC-MS(n) approaches. Targeted approaches identified major anthocyanin and ellagitannin components at varying recoveries and with considerable interindividual variation. Nontargeted LC-MS(n) analysis using an orbitrap mass spectrometer gave exact mass MS data which were sifted using a software program to select peaks that changed significantly after supplementation. This method confirmed the recovery of the targeted components but also identified novel raspberry-specific metabolites. Some components (including ellagitannin and previously unidentified proanthocyanidin derivatives) may have arisen from raspberry seeds that survived intact in ileal samples. Other components include potential breakdown products of anthocyanins, unidentified components, and phenolic metabolites formed either in the gut epithelia or after absorption into the circulatory system and efflux back into the gut lumen. The possible physiological roles of the ileal metabolites in the large bowel are discussed

Item Type:Journal article
Keywords:Polyphenols, digestion, ileal fluid, raspberries, diet, gut health
Faculties and Schools:Faculty of Life and Health Sciences > School of Biomedical Sciences
Faculty of Life and Health Sciences
Research Institutes and Groups:Biomedical Sciences Research Institute > Nutrition Innovation Centre for Food and Health (NICHE)
Biomedical Sciences Research Institute
ID Code:32185
Deposited By: Dr Chris Gill
Deposited On:25 Aug 2015 15:50
Last Modified:25 Aug 2015 15:50

Repository Staff Only: item control page