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Electrochemical bubble rip: A new approach to controlled drug release

Anderson, A, McConville, A and Davis, J (2015) Electrochemical bubble rip: A new approach to controlled drug release. Electrochemistry Communications, 60 . pp. 88-91. [Journal article]

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DOI: doi:10.1016/j.elecom.2015.08.008

Abstract

Cellulose acetate phthalate films are widely used as controlled release enteric coatings within the pharmaceutical industries but their properties have hitherto been unexplored within electrochemical devices. A novel approach employing controlled electrolysis has been investigated to develop a means through which the protective films can be compromised thereby enabling the release of candidate drugs. The generation of bubbles and local pH manipulation are considered and the former shown to enable rapid removal of the film and initiate reagent release.

Item Type:Journal article
Keywords:electrode, drug release, cellulose acetate phthalate chemotherapy
Faculties and Schools:Faculty of Computing & Engineering
Faculty of Computing & Engineering > School of Engineering
Research Institutes and Groups:Engineering Research Institute
Engineering Research Institute > Nanotechnology & Integrated BioEngineering Centre (NIBEC)
ID Code:32621
Deposited By: Professor James Davis
Deposited On:26 Nov 2015 12:38
Last Modified:26 Nov 2015 12:38

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