Ulster University Logo

Physical rehabilitation interventions for adult patients during critical illness: an overview of systematic reviews

Connolly, B, O'Neill, Brenda, Salisbury, L and Blackwood, B (2016) Physical rehabilitation interventions for adult patients during critical illness: an overview of systematic reviews. Thorax, 71 . pp. 881-890. [Journal article]

[img] Text - Accepted Version
[img] Text - Supplemental Material
Restricted to Repository staff only


URL: http://dx.doi.org/10.1136/thoraxjnl-2015-208273

DOI: 10.1136/thoraxjnl-2015-208273


Background: Physical rehabilitation interventions aim to ameliorate the effects of critical illness-associated muscle dysfunction in survivors. We conducted an overview of systematic reviews (SR) evaluating the effect of these interventions across the continuum of recovery. Methods: Six electronic databases (Cochrane Library, CENTRAL, DARE, Medline, Embase, and Cinahl) were searched. Two review authors independently screened articles for eligibility and conducted data extraction and quality appraisal. Reporting quality was assessed and the Grading of Recommendations Assessment, Development and Evaluation approach applied to summarise overall quality of evidence. Results: Five eligible SR were included in this overview, of which three included meta-analyses. Reporting quality of the reviews was judged as medium to high. Two reviews reported moderate-to-high quality evidence of the beneficial effects of physical therapy commencing during intensive care unit (ICU) admission in improving critical illness polyneuropathy/myopathy, quality of life, mortality and healthcare utilisation. These interventions included early mobilisation, cycle ergometry and electrical muscle stimulation. Two reviews reported very low to low quality evidence of the beneficial effects of electrical muscle stimulation delivered in the ICU for improving muscle strength, muscle structure and critical illness polyneuropathy/myopathy. One review reported that due to a lack of good quality randomised controlled trials and inconsistency in measuring outcomes, there was insufficient evidence to support beneficial effects from physical rehabilitation delivered post-ICU discharge.Conclusions: Patients derive short-term benefits from physical rehabilitation delivered during ICU admission. Further robust trials of electrical muscle stimulation in the ICU and rehabilitation delivered following ICU discharge are needed to determine the long-term impact on patient care. This overview provides recommendations for design of future interventional trials and SR. Trial registration number: CRD42015001068.

Item Type:Journal article
Keywords:Critical illness, physical rehabilitation, recovery, systematic review, quality
Faculties and Schools:Faculty of Life and Health Sciences
Faculty of Life and Health Sciences > School of Health Sciences
Research Institutes and Groups:Institute of Nursing and Health Research > Centre for Health and Rehabilitation Technologies
Institute of Nursing and Health Research
ID Code:35178
Deposited By: Dr Brenda O'Neill
Deposited On:28 Jul 2016 14:48
Last Modified:22 Apr 2018 12:09

Repository Staff Only: item control page