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Microneedle drug delivery systems: Appraising opportunities for improving safety and assessing areas of concern

Chege, Martha, McConville, Aaron and Davis, James (2017) Microneedle drug delivery systems: Appraising opportunities for improving safety and assessing areas of concern. Journal of Chemical Health and Safety, 24 (2). pp. 6-14. [Journal article]

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DOI: 10.1016/j.jchas.2016.04.008

Abstract

Transdermal microneedles are regularly advocated as a much safer alternative to conventional hypodermic injections and an ever increasing range of systems are being developed. While there are clear advantages to their adoption, there are a number of safety issues that are emerging which have short and long term implications for patients, clinicians, healthcare administrators and regulators. A brief overview of microneedle design is presented and considered in a critical light in comparison to conventional drug delivery routes. The focus is not on drug safety but rather on the safety concerns of the actual delivery processes for patient and healthcare practitioner. The safety benefits that these new approaches offer and the potential safety concerns that still need to be addressed are highlighted and the possible implications critically assessed.

Item Type:Journal article
Keywords:microneedle, safety, transdermal, drug delivery
Faculties and Schools:Faculty of Computing & Engineering
Faculty of Computing & Engineering > School of Engineering
Research Institutes and Groups:Engineering Research Institute
Engineering Research Institute > Nanotechnology & Integrated BioEngineering Centre (NIBEC)
ID Code:35680
Deposited By: Professor James Davis
Deposited On:19 Aug 2016 14:40
Last Modified:08 Jun 2017 15:52

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