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Habitat, applications and genomics of the aerobic, thermophilic genus Geobacillus

McMullan, Geoffrey, Christie, JM, Rahman, TJ, Banat, Ibrahim, Ternan, Nigel and Marchant, Roger (2004) Habitat, applications and genomics of the aerobic, thermophilic genus Geobacillus. BIOCHEMICAL SOCIETY TRANSACTIONS, 32 (Part 2). pp. 214-217. [Journal article]

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URL: http://www.biochemsoctrans.org/bst/032/0214/0320214.pdf


Thermophilic bacteria belonging to Bacillus genetic group 5 have been reclassified as being members of Geobacillus gen. nov., with G. stearothermophilus as the type strain. Geobacillus species, literally meaning earth or soil Bacillus, are widely distributed and readily isolated from natural and man-made thermophilic biotopes. Work within our group has however shown that an abundance of genetically distinct Geobacillus isolates can be obtained from temperate Irish soils. As with many thermophiles there is considerable interest in potential industrial application of these bacteria and their gene products. This review describes two novel applications for Geobacillus isolates, firstly in the metabolism of the herbicide glyphosate and secondly in the metabolism of quorum-sensing signal molecules from Gram-negative bacteria. Finally the current state of the art is described for Bacillus genomics, with details given of three independent genome-sequencing projects of Geobacillus isolates.

Item Type:Journal article
Faculties and Schools:Faculty of Life and Health Sciences
Faculty of Life and Health Sciences > School of Biomedical Sciences
Research Institutes and Groups:Biomedical Sciences Research Institute > Nutrition Innovation Centre for Food and Health (NICHE)
Biomedical Sciences Research Institute
Biomedical Sciences Research Institute > Pharmacy & Pharmaceutical Sciences
ID Code:3681
Deposited By: Dr Nigel Ternan
Deposited On:17 Dec 2009 14:07
Last Modified:16 May 2012 14:09

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