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Iodinated Cyanine Dyes: A New Class of Sensitisers for use in NIR Activated Photodynamic Therapy (PDT)

Callan, John, Atchison, Jordan, Kamila, Sukanta, Logan, Kieran, Nicholas, Dean, Fowley, Colin, Davis, James, Callan, Bridgeen and McHale, Anthony (2017) Iodinated Cyanine Dyes: A New Class of Sensitisers for use in NIR Activated Photodynamic Therapy (PDT). Chemical Communications, 53 (12). pp. 2009-2012. [Journal article]

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DOI: 10.1039/C6CC09624G

Abstract

A new class of iodinated cyanine dyes have been prepared for use in NIR excited photodynamic therapy (PDT) and demonstrated improved efficacy in three pancreatic cell lines as well as excellent tumour control in a murine model of the disease.

Item Type:Journal article
Keywords:PDT, sensitiser, NIR, pancreatic cancer
Faculties and Schools:Faculty of Computing & Engineering
Faculty of Life and Health Sciences > School of Pharmacy and Pharmaceutical Science
Faculty of Computing & Engineering > School of Engineering
Faculty of Life and Health Sciences
Research Institutes and Groups:Engineering Research Institute
Engineering Research Institute > Nanotechnology & Integrated BioEngineering Centre (NIBEC)
Biomedical Sciences Research Institute
Biomedical Sciences Research Institute > Pharmacy & Pharmaceutical Sciences
ID Code:37569
Deposited By: Professor John Callan
Deposited On:25 Apr 2017 13:56
Last Modified:18 Jan 2018 23:23

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