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Me-D-Links: Metformin for diabetes in pregnancy – an analysis of health and education outcomes using linked administrative data

Given, Joanne, Coates, Vivien, Bunting, Brendan, Loane, Maria, Garne, Ester, O'Connor Bones, Una, McCance, David and Dolk, Helen (2017) Me-D-Links: Metformin for diabetes in pregnancy – an analysis of health and education outcomes using linked administrative data. In: ADRN2017 (The UK Administrativer Data Research Network Annual Research Conference), Edinburgh. Administrativ Data Research Network. 1 pp. [Conference contribution]

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Abstract

Traditionally insulin has been considered the ‘gold standard’ for the treatment of diabetes in pregnancy but since 2015 the UK guidelines have also recommended metformin, an oral blood glucose lowering drug. The routine use of metformin in pregnancy is however controversial. Metformin has been shown to cross the placenta and we do not know if it affects the growth or long term development of children who were exposed in the womb. With increasing numbers of women in the UK taking metformin during their pregnancy more research is needed to determine its potential harms or benefits. This study aims to use routinely collected administrative data to explore the effect of metformin on maternal and infant health and early childhood educational achievement.As metformin is not commonly used in pregnancy, and some of the pregnancy complications in which we are interested are rare, it is necessary to use data from as large an area as possible. Through the Administrative Data Research Network (ADRN) we aim to access prescribing records, mother and child health records and educational records from all 4 regions of the UK. The outcomes among pregnant women, or infants, who were exposed to metformin will then be compared to those who were not.The findings of this research will help women and their health care providers make more informed decisions about their care. As one of the first, if not the first, projects conducted within the ADRN using data from all 4 regions of the UK this project will also help to clarify the processes involved and assist in the design and conduct of future UK wide projects.

Item Type:Conference contribution (Lecture)
Keywords:Metfromin Pregnancy Educational attainment Birth
Faculties and Schools:Faculty of Social Sciences > School of Education
Faculty of Life and Health Sciences > School of Nursing
Faculty of Life and Health Sciences
Faculty of Life and Health Sciences > School of Psychology
Faculty of Social Sciences
Research Institutes and Groups:Institute of Nursing and Health Research > Centre for Maternal, Fetal and Infant Research
Psychology Research Institute > Population Health Sciences and Mental Health Services
Psychology Research Institute
Institute of Nursing and Health Research
Institute for Research in Social Sciences > Education
Institute of Nursing and Health Research > Managing Chronic Illness Research Centre
Institute for Research in Social Sciences
ID Code:38135
Deposited By: Dr Joanne Given
Deposited On:13 Jun 2017 13:34
Last Modified:17 Oct 2017 16:30

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