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Salicylate Poisoning Potential of Topical Pain Relief Agents: From Age Old Remedies to Engineered Smart Patches

Anderson, Ashleigh, McConville, Aaron, Fanthorpe, Laura and Davis, James (2017) Salicylate Poisoning Potential of Topical Pain Relief Agents: From Age Old Remedies to Engineered Smart Patches. Medicinces, 4 (3). p. 48. [Journal article]

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DOI: 10.3390/medicines4030048

Abstract

The pain relief capabilities of methyl salicylate are well established and a multitude of over-the-counter products populate pharmacy shelves. Over-application of the topical preparation containing the drug, or its accidental ingestion, invariably result in salicylate poisoning and in severe cases can be fatal. The drug has been a regular feature of the US National Poison Database Survey over the past decade and continues to pose a risk to children and adults alike. The aim of the review has been to cast a spotlight on the drug and assess why its use remains problematic, how technology could offer more efficacious delivery regimes, and minimise the possibility of accidental or intentional misuse.

Item Type:Journal article
Keywords:smart patches; methyl salicylate; toxicity; microneedle; transdermal
Faculties and Schools:Faculty of Computing & Engineering
Faculty of Computing & Engineering > School of Engineering
Research Institutes and Groups:Engineering Research Institute
Engineering Research Institute > Nanotechnology & Integrated BioEngineering Centre (NIBEC)
ID Code:38354
Deposited By: Professor James Davis
Deposited On:19 Jul 2017 13:47
Last Modified:17 Oct 2017 16:30

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