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Comparative study of surface properties of Mg-substituted hydroxyapatitebioceramic microspheres

Stipniece, Liga, Stepanova, Valentina, Narkevica, Inga, Salma-Ancane, Kristine and Boyd, Adrian (2017) Comparative study of surface properties of Mg-substituted hydroxyapatitebioceramic microspheres. Journal of the European Ceramic Society, 37 . [Journal article]

[img] Text - Accepted Version
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URL: http://dx.doi.org/10.1016/j.jeurceramsoc.2017.09.026

DOI: 10.1016/j.jeurceramsoc.2017.09.026


Mg-substituted hydroxyapatite (HAp) bioceramic microspheres were prepared by spray drying and subsequent processing at 1173, 1273 and 1373 K. Influence of various Mg substitution levels (up to 0.84 ± 0.10 wt%) on physicochemical properties of the HAp bioceramic microspheres was evaluated. Obtained results were used for the elucidation of the compositional and structural characteristics of the microspheres in conjunction with adsorption of protein, namely, bovine serum albumin (BSA). The primary difference among the microspheres processed at various temperature was the presence or absence of the micropores (< 2 nm in diameter) and mesopores (between 2 and 50 nm). Presence of the micro- and mesopores resulted in higher specific surface area (SSA), enhanced solubility, i.e., ion release, and, accordingly, increase in the amount of BSA adsorbed on the microspheres. Furthermore, the BSA adsorption capacity of the microspheres decreased with increasing Mg content despite of higher SSA.

Item Type:Journal article
Keywords:Hydroxyapatite, Bioceramic, Microspheres, Mg substitution, Protein adsorption
Faculties and Schools:Faculty of Computing & Engineering
Faculty of Computing & Engineering > School of Engineering
Research Institutes and Groups:Engineering Research Institute
Engineering Research Institute > Nanotechnology & Integrated BioEngineering Centre (NIBEC)
ID Code:38719
Deposited By: Dr Adrian Boyd
Deposited On:24 Oct 2017 14:11
Last Modified:24 Oct 2017 14:11

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