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Rapid Determination of Salicylic Acid at Screen Printed Electrodes

Rawlinson, Sean, McLister, Anna, Kanyong, Prosper and Davis, James (2018) Rapid Determination of Salicylic Acid at Screen Printed Electrodes. Microchemical Journal, 137 . pp. 71-77. [Journal article]

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DOI: 10.1016/j.microc.2017.09.019

Abstract

The pain relief capabilities of salicylate are well established and a multitude of over the counter products populate pharmacy shelves. Over application of the preparations, through accidental or deliberate misuse, can all too often result in salicylate poisoning and, in severe cases, can be fatal. A novel detection strategy involving the quantification of the quinone byproducts arising from the electrochemical oxidation of salicylate is described. The approach has been adapted for use with a disposable screen-printed electrode and found to exhibit a high sensitivity towards salicylate which is free from the electroactive interferences that compromise the direct oxidative route. A linear range of 16 to 300 M was observed with a limit of detection of 5.6 M. The analytical applicability of the approach was demonstrated through recovery experiments of 100 M salicylate in urine.

Item Type:Journal article
Keywords:Sensor; Salicylate Poisoning; Electrode
Faculties and Schools:Faculty of Computing & Engineering
Faculty of Computing & Engineering > School of Engineering
Research Institutes and Groups:Engineering Research Institute
Engineering Research Institute > Nanotechnology & Integrated BioEngineering Centre (NIBEC)
ID Code:39043
Deposited By: Professor James Davis
Deposited On:08 Jan 2018 11:21
Last Modified:21 Feb 2018 16:14

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