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Label free detection of Prostate Specific Antigen at a screen printed immunosensor modified with a nano-structured gold layer

rawlinson, Sean, Kanyong, Prosper, McConville, Aaron, Fearon, John-Joe, McLaughlin, James and Davis, James (2017) Label free detection of Prostate Specific Antigen at a screen printed immunosensor modified with a nano-structured gold layer. Chemistry Letters, 46 (12). pp. 1728-1731. [Journal article]

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DOI: 10.1246/cl.170790

Abstract

The development of a disposable immunosensor based on a hybrid gold-carbon screen printed electrode array is described. The electrodeposition of gold is shown to lead to a field of nanocrystals that facilitates antibody immobilization and enhances electron transfer. A label free analysis protocol based on ferrocyanide has been developed for the detection of Prostate Specific Antigen in the fg/mL range.

Item Type:Journal article
Keywords:PSA ; Prostate Cancer; Sensor; Electrode
Faculties and Schools:Faculty of Computing & Engineering
Faculty of Computing & Engineering > School of Engineering
Research Institutes and Groups:Engineering Research Institute
Engineering Research Institute > Nanotechnology & Integrated BioEngineering Centre (NIBEC)
ID Code:39044
Deposited By: Professor James Davis
Deposited On:08 Jan 2018 11:22
Last Modified:08 Jan 2018 11:22

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