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Microneedle Manufacture: Assessing Hazards and Control Measures

Martin, Alexander, McConville, Aaron, Anderson, Ashleigh, McLister, Anna and Davis, James (2017) Microneedle Manufacture: Assessing Hazards and Control Measures. Safety, 3 . [Journal article]

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DOI: 10.3390/safety3040025

Abstract

Transdermal microneedles have captured the attention of researchers in relation to a variety of applications, and silicone-based moulds required to produce these systems are now widely available and can be readily manufactured on the lab bench. There is however some concern overthe potential for accidental needlestick injuries and, as with any sharp hazard, the potential for blood-borne pathogen transmission must be considered. This follows from recent governmental concerns over the use of microneedle systems in dermabrasion. Despite the piercing nature of the microneedle patch sharing many similarities with conventional hypodermic needles, there are notable factors that mitigate the risk of contamination. A range of microneedle systems has been prepared using micromoulding techniques, and their puncture capability assessed. A critical assessment of the potential for accidental puncture and the control measures needed to ensure safe utilisation of the patch systems is presented.

Item Type:Journal article
Keywords:Microneedle; Safety; Needlestick; Manufacture
Faculties and Schools:Faculty of Computing & Engineering
Faculty of Computing & Engineering > School of Engineering
Research Institutes and Groups:Engineering Research Institute
Engineering Research Institute > Nanotechnology & Integrated BioEngineering Centre (NIBEC)
ID Code:39045
Deposited By: Professor James Davis
Deposited On:08 Jan 2018 11:23
Last Modified:08 Jan 2018 11:23

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