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Diet, nutrition and the ageing brain: current evidence and new directions

Moore, Katie, Hughes, Catherine, Ward, Mary, Hoey, Leane and McNulty, Helene (2018) Diet, nutrition and the ageing brain: current evidence and new directions. Proceedings of the Nutrition Society, NA . [Journal article]

[img] Text - Published Version

URL: https://www.cambridge.org/core/journals/proceedings-of-the-nutrition-society/article/diet-nutrition-and-the-ageing-brain-current-evidence-and-ne w-directions/8378A6954F727E4680508A7DF5796D03

DOI: doi:10.1017/S0029665117004177


Globally populations are ageing. By 2050, it is estimated that there will be two billion people aged 60 years or over, of which 131 million are projected to be affected by dementia, while depression is predicted to be the second leading cause of disability worldwide by 2020. Preventing or delaying the onset of these disorders should therefore be a public health priority. There is some evidence linking certain dietary patterns, particularly the Mediterranean diet, with a reduced risk of dementia and depression. Specific dietary components have also been investigated in relation to brain health, with emerging evidence supporting protective roles for n-3 PUFA, polyphenols, vitamin D and B-vitamins. At this time, the totality of evidence is strongest in support of a role for folate and the metabolically related B-vitamins (vitamin B12, vitamin B6 and riboflavin) in slowing the progression of cognitive decline and possibly reducing the risk of depression in ageing. Future studies incorporating new technologies, such as MRI and magnetoencephalography, offer much promise in identifying effective nutrition interventions that could reduce the risk of cognitive and mental disorders. This review will explore the ageing brain and the emerging evidence linking diet and specific nutrients with cognitive function and depression in ageing, with the potential to develop strategies that could improve quality of life in our ageing population.

Item Type:Journal article
Keywords:Nutrition: Cognition: Depression: Ageing: B-vitamins
Faculties and Schools:Faculty of Life and Health Sciences > School of Biomedical Sciences
Faculty of Life and Health Sciences
Research Institutes and Groups:Biomedical Sciences Research Institute > Nutrition Innovation Centre for Food and Health (NICHE)
Biomedical Sciences Research Institute
ID Code:40046
Deposited By: Miss Katie Moore
Deposited On:25 Apr 2018 11:32
Last Modified:10 Jan 2019 23:23

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