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Luminescent sensing with quantum dots

Callan, John F., De Silva, A. P., Mulrooney, R. C. and McCaughan, B. (2007) Luminescent sensing with quantum dots. JOURNAL OF INCLUSION PHENOMENA AND MACROCYCLIC CHEMISTRY, 58 (3-4). pp. 257-262. [Journal article]

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DOI: 10.1007/s10847-006-9152-8


This review highlights recent advances in the use of quantum dots (QD's) as luminescent sensors. The bulk of the study concentrates on systems that possess organic ligands bound to the surface of QD's. These ligands vary from low molecular weight thiols to larger molecules such as maltose binding protein. All have one thing in common: when a target analyte binds to the ligand/receptor, a perturbation of the system occurs, that registers itself as a change in the luminescence intensity of the QD. Two main mechanisms are prevalent in controlling the luminescent intensity in such systems. The first is Photoinduced Electron Transfer (PET) and the second energy transfer. This review looks at current sensors that operate by using these mechanisms. Two component systems are also investigated where a quencher is first added to a solution of the QD, followed by addition of the target analyte that interacts with the quencher to influence the luminescence intensity.

Item Type:Journal article
Faculties and Schools:Faculty of Life and Health Sciences > School of Pharmacy and Pharmaceutical Science
Faculty of Life and Health Sciences
Research Institutes and Groups:Biomedical Sciences Research Institute
Biomedical Sciences Research Institute > Pharmacy & Pharmaceutical Sciences
ID Code:4072
Deposited By: Professor John Callan
Deposited On:05 Jan 2010 10:21
Last Modified:19 Nov 2012 15:26

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