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Acute effects of walking on inflammatory and cardiovascular risk in sedentary post-menopausal women

Davis, Gillian, Murphy, Marie, Trinick, Tom, Duly, Ellie, Nevill, Alan and Davison, Gareth (2008) Acute effects of walking on inflammatory and cardiovascular risk in sedentary post-menopausal women. Journal of Sports Sciences, 26 (3). pp. 303-309. [Journal article]

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DOI: 10.1080/02640410701552906


Biochemical markers of inflammation are emerging as new predictors of risk of cardiovascular disease (CVD) and may alteracutely with exercise. Few studies have been conducted on the effects of walking on these markers or whether differentwalking intensities elicit varied effects. As there is growing interest in modifiable lifestyle factors such as walking to reduceCVD risk, these inflammatory responses warrant investigation. The aim of this study was to compare the effects of walking at50% versus 70% of predicted maximal heart rate on C-reactive protein (CRP), plasma fibrinogen, and trigylcerides insedentary post-menopausal women. Twelve post-menopausal women (mean age 58 years, s+6; stature 1.62 m, s+0.06;body mass 66.8 kg, s+6.2) completed two 30-min treadmill walks in a randomized cross-over design. Fasted blood sampleswere taken (for the determination of plasma fibrinogen, CRP, and lipids) before, immediately after, and 1 and 24 h afterexercise. Triglyceride concentrations decreased from pre-exercise to 24 h post exercise at both walking intensities(time6group interaction, P50.05). No significant effects were observed for plasma fibrinogen, CRP, total cholesterol, lowdensityor high-density lipoprotein cholesterol (time x group interaction, P40.05). The results of this study suggest thatfasting plasma triglycerides are decreased on the morning after 30 min of brisk walking at either 50% or 70% of maximalheart rate (moderate and vigorous intensity).

Item Type:Journal article
Faculties and Schools:Faculty of Life and Health Sciences
Faculty of Life and Health Sciences > School of Sport
Research Institutes and Groups:Sport and Exercise Sciences Research Institute
Sport and Exercise Sciences Research Institute > Centre for Physical Activity and Health
ID Code:5750
Deposited By: Professor Gareth Davison
Deposited On:04 Feb 2010 15:48
Last Modified:29 Oct 2012 15:55

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