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Photocatalytic inactivation of Cryptosporidium parvum on nanostructured titanium dioxide films

Sunnotel, O, Verdoold, R, Dunlop, PSM, Snelling, WJ, Lowery, C, Dooley, J, Moore, JE and Byrne, JA (2010) Photocatalytic inactivation of Cryptosporidium parvum on nanostructured titanium dioxide films. Journal of Water and Health, 08 (1). p. 83. [Journal article]

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URL: http://dx.doi.org/10.2166/wh.2009.204

DOI: doi:10.2166/wh.2009.204


Control of waterborne gastrointestinal parasites represents a major concern to water industries worldwide. In developed countries, pathogens in drinking water supplies are normally removed by sand filtration followed by chemical disinfection. Cryptosporidium spp. are generally resistant to common disinfection techniques and alternative control strategies are being sought. In the current study, the photocatalytic inactivation of C. parvum oocysts was shown to occur in buffer solution (78.4% after 180 min) and surface water (73.7% after 180 min). Viability was assessed by dye exclusion, excystation, direct examination of oocysts and a novel gene expression assay based on lactate dehydrogenase 1 (LDH1) expression levels. Collectively, this confirmed the inactivation of oocysts and scanning electron microscopy (SEM) confirmed cleavage at the suture line of oocyst cell walls, revealing large numbers of empty (ghost) cells after exposure to photocatalytic treatment.

Item Type:Journal article
Faculties and Schools:Faculty of Computing & Engineering
Faculty of Life and Health Sciences > School of Biomedical Sciences
Faculty of Life and Health Sciences
Faculty of Computing & Engineering > School of Engineering
Research Institutes and Groups:Biomedical Sciences Research Institute > Nutrition Innovation Centre for Food and Health (NICHE)
Engineering Research Institute
Engineering Research Institute > Nanotechnology & Integrated BioEngineering Centre (NIBEC)
Biomedical Sciences Research Institute
ID Code:7508
Deposited By: Dr Patrick Dunlop
Deposited On:18 Jan 2010 12:13
Last Modified:13 Mar 2018 16:01

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