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Number of items: 28.


Byrne, NM, Nesbitt, Heather, Ming, L, McKeown, Stephanie, Worthington, Jenny and McKenna, Declan (2016) Androgen deprivation in LNCaP prostate tumour xenografts induces vascular changes and hypoxic stress, resulting in promotion of epithelial-to-mesenchymal transition. British Journal of Cancer, epub . [Journal article]


Nesbitt, Heather, Browne, Gillian, O'Donovan, Katie M., Byrne, Niall M., Worthington, Jenny, McKeown, Stephanie and McKenna, Declan J (2015) Nitric Oxide Up-Regulates RUNX2 in LNCaP Prostate Tumours: Implications for Tumour Growth In Vitro and In Vivo. Journal of Cellular Physiology, 231 (2). pp. 473-482. [Journal article]

Nesbitt, Heather, byrne, niall, Worthington, Jenny, McKeown, Stephanie and McKenna, Declan (2015) Targeting hypoxia in prostate cancer cells to increase treatment efficacy. Ulster Medical Journal, 84 (3). pp. 209-210. [Journal article]

Smith, Paul, Wiltshire, Marie, Nesbitt, Heather, Byrne, Niall, Ming, Louise, McKenna, Declan, Worthington, Jenny, McKeown, Stephanie, Patterson, Laurence and Errington, Rachel (2015) Cytometry of Anticancer Prodrug OCT1002 Activation and Targeting Using In Vitro and In Vivo Models of Tumour Hypoxia. In: CYTO 2015, the 30th Congress of the International Society for Advancement of Cytometry, Glasgow,Scotland. International Society for Advancement of Cytometry. 268 pp. [Conference contribution]

cochrane, david, o'donovan, katie, Nesbitt, Heather, McKeown, Stephanie, Worthington, Jenny, o'rourke, martin, James, Iain and McKenna, Declan (2015) Characterisation of novel AKT inhibitor in treatment of androgen sensitive prostate cancer. In: Irish Association for Cancer Research 2015, Limerick. Irish Association for Cancer Research. 180 pp. [Conference contribution]


Moore, Johnny E, Atkinson, Sarah D, Azar, Dimitri T, Worthington, Jenny, Downes, C Stephen, Courtney, David G and Moore, C.B Tara (2014) Protection of corneal epithelial stem cells prevents UV-A damage during corneal collagen cross-linking treatment for keratoconus. Br J Ophthalmol, 98 (2). pp. 270-274. [Journal article]

Rashid, Shazia, Unyayar, Ali, Mazmanci, Mehmet Ali, McKeown, Stephanie R., Worthington, Jenny and Banat, Ibrahim (2014) Potential of a Funalia trogii laccase enzyme as an anticancer agent. Ann Microbiol (2015) 65:175–183, 65 . pp. 175-183. [Journal article]


Burns, Jorge Sans, Yakkundi, Anita, McCallum, Lynn, O’Kane, Anthony, Dyer, Hayder, Worthington, Jenny, McKeen, Hayley D., McClements, Lana, Elliott, Christopher, McCarthy, Helen O., Hirst, David G. and Robson, Tracy (2013) The Anti-Migratory Effects of FKBPL and Its Peptide Derivative, AD-01: Regulation of CD44 and the Cytoskeletal Pathway. PLoS ONE, 8 (2). e55075. [Journal article]

Hussain, AI, Anwar, F, Chatha, SAS, Latif, S, Sherazi, STH, Ahmad, A, Worthington, Jenny and Sarker, SD (2013) Chemical composition and bioactivity studies of the essential oils from two Thymus species from the Pakistani flora. LWT- Food Science and Technology, 50 (1). pp. 185-192. [Journal article]

Ming, L, Byrne, N, Camac, SN, Ward, C, Mitchell, Christopher, Waugh, D, McKeown, Stephanie and Worthington, Jenny (2013) Androgen deprivation results in time-dependent hypoxia in LNCaP prostate tumours; informed scheduling of the bioreductive drug AQ4N improves treatment response. International Journal of Cancer, 132 . pp. 1323-1332. [Journal article]


Browne, G, Nesbitt, H, Ming, L, Stein, GS, Lian, JB, McKeown, SR and Worthington, Jenny (2012) Bicalutamide-induced hypoxia potentiates RUNX2-mediated Bcl-2 expression resulting in apoptosis resistance. British Journal of Cancer, 107 . pp. 1714-1721. [Journal article]


Valentine, A., O'Rourke, M, Yakkundi, A, Worthington, Jenny, Hookham, M, Bicknall, R, McCarthy, HO, McClelland, K, McCallum, L, Dyer, H, McKeen, H, Waugh, DJ, Roberts, J, McGregor, J, Cotton, G, James, I, Harrison, T, Hirst, DG and Robson, T (2011) FKBPL and Peptide Derivatives: Novel Biological AgentsThat Inhibit Angiogenesis by a CD44-Dependent Mechanism. Clinical Cancer Research, 17 (5). pp. 1044-1056. [Journal article]

Worthington, Jenny, McKeown, Stephanie and Banat, Ibrahim (2011) A study of anti-cancer effects of Funalia trogii in vitro and in vivo. Food and Chemical Toxicology, 49 (7). pp. 1477-1483. [Journal article]


Adams, Catherine, McCarthy, Helen O., Coulter, Jonathan A., Worthington, Jenny, Murphy, Claire, Robson, Tracy and Hirst, Davi G. (2009) Nitric oxide synthase gene therapy enhances the toxicity of cisplatin in cancer cells. JOURNAL OF GENE MEDICINE, 11 (2). pp. 160-168. [Journal article]

Worthington, Jenny and Rashid, Shazia (2009) The therapeutic potential of mushroom extracts. In: Natural Products as future therapeutic agents. Old City Publishing, pp. 49-72. ISBN 978-81-7895-394-6 [Book section]


Butterworth, Karl T, McCarthy, Helen O, Devlin, Andrea, Ming, Louise, Robson, Tracy, McKeown, Stephanie and Worthington, Jenny (2008) Hypoxia selects for androgen independent LNCaP cells with a more malignant geno- and phenotype. INTERNATIONAL JOURNAL OF CANCER, 123 (4). pp. 760-768. [Journal article]

Coulter, J. A., McCarthy, H. O., Worthington, Jenny, Robson, T., Scott, S. and Hirst, D. G. (2008) The radiation-inducible pE9 promoter driving inducible nitric oxide synthase radiosensitizes hypoxic tumour cells to radiation. GENE THERAPY, 15 (7). pp. 495-503. [Journal article]

Marignol, L., Robson, T., McCarthy, H. O., Worthington, Jenny, Murray, M. M., Hollywood, D., Lawler, M. and Hirst, D. G. (2008) The tissue plasminogen activator gene promoter: a novel tool for radiogenic gene therapy of the prostate? JOURNAL OF GENE MEDICINE, 10 (9). pp. 1032-1038. [Journal article]

O'Rourke, Martin, Ward, Claire, Worthington, Jenny, McKenna, Julie, Valentine, Andrea, Robson, Tracy, Hirst, David G and McKeown, Stephanie (2008) Evaluation of the antiangiogenic potential of AQ4N. CLINICAL CANCER RESEARCH, 14 (5). pp. 1502-1509. [Journal article]

Wilson, C, Scullin, P, Worthington, Jenny, Seaton, A, Maxwell, P, O'Rourke, D, Johnston, PG, McKeown, Stephanie, Wilson, RH, O'Sullivan, JM and Waugh, DJJ (2008) Dexamethasone potentiates the antiangiogenic activity of docetaxel in castration-resistant prostate cancer. BRITISH JOURNAL OF CANCER, 99 (12). pp. 2054-2064. [Journal article]


McCarthy, HO, Worthington, Jenny, Barrett, E, Cosimo, E, Boyd, M, Mairs, RJ, Ward, C, McKeown, Stephanie, Hirst, DG and Robson, T (2007) p(21(WAF1))-mediated transcriptional targeting of inducible nitric oxide synthase gene therapy sensitizes tumours to fractionated radiotherapy. GENE THERAPY, 14 (3). pp. 246-255. [Journal article]

McCarthy, Helen O., Coulter, Jonathan A., Worthington, Jenny, Robson, Tracy and Hirst, David G. (2007) Human osteocalcin: a strong promoter for nitric oxide synthase gene therapy, with specificity for hormone refractory prostate cancer. JOURNAL OF GENE MEDICINE, 9 (6). pp. 511-520. [Journal article]


Robson, T, Worthington, Jenny, McKeown, Stephanie and Hirst, DG (2005) Radiogenic therapy: Novel approaches for enhancing tumor radiosensitivity. TECHNOLOGY IN CANCER RESEARCH & TREATMENT, 4 (4). pp. 343-361. [Journal article]

Worthington, J, Robson, T, Scott, S and Hirst, D (2005) Evaluation of a synthetic CArG promoter for nitric oxide synthase gene therapy of cancer. GENE THERAPY, 12 (19). pp. 1417-1423. [Journal article]


McCarthy, HO, Worthington, Jenny, Ward, C, Barrett, E, Hirst, DG, McKeown, Stephanie and Robson, T (2004) Use of the p2l/WAF1 promoter for transcriptional targetting in cancer gene therapy. JOURNAL OF GENE MEDICINE, 6 (9). p. 78. [Journal article]

Worthington, Jenny, McCarthy, HO, Barrett, E, Adams, C, Robson, T and Hirst, DG (2004) Use of the radiation-inducible WAF1 promoter to drive iNOS gene therapy as a novel anti-cancer treatment. JOURNAL OF GENE MEDICINE, 6 (6). pp. 673-680. [Journal article]


Worthington, Jenny, Robson, T, O'Keeffe, M and Hirst, DG (2002) Tumour cell radiosensitization using constitutive (CMV) and radiation inducible (WAF1) promoters to drive the iNOS gene: a novel suicide gene therapy. GENE THERAPY, 9 (4). pp. 263-269. [Journal article]


Worthington, Jenny, Robson, T, Murray, M, O'Rourke, M, Keilty, G and Hirst, DG (2000) Modification of vascular tone using iNOS under the control of a radiation-inducible promoter. GENE THERAPY, 7 (13). pp. 1126-1131. [Journal article]

This list was generated on Sun Sep 22 01:39:49 2019 BST.